J Urol. 2013 Jan 30. pii: S0022-5347(13)00227-9. doi: 10.1016/j.juro.2013.01.087. [Epub ahead of print]
Another study published using xiaflex. Preliminary results continue to show that it does very little to resolve penile tortuosity.
The patients were divided into two groups in this study. One group received an injection of xiaflex into the penis and the other received an injection of saline (placebo).
The group that received xiaflex had an average tortuosity of 50,1After 52 weeks of treatment (8 applications) they had a curvature of 33,1The individuals in the second group had an initial tortuosity of 49,3At the end of the treatment she was 40o.
The conclusion is that xiaflex only reduces 7,7after 52 weeks of invasive treatment, when compared to placebo.
It was noted that 84.2% of the patients who used xiaflex had a local adverse reaction, such as pain, redness, bruising, swelling, etc.
Of the 558 patients treated with the drug, 3 had to undergo emergency surgery due to rupture of the tunica albuginea (inner part of the penis), which had been eroded by the medication.
The impression we get at the end is that it's a drug that causes a lot of side-effects and has low resolutivity, as it only rectifies 7,7compared to placebo.
